Jack L Ferracane, PhD

Jack Ferracane is Professor and Chair of the Department of Oral Rehabilitation and Biosciences at Oregon Health & Science University, Portland, Oregon.  He received a B.S. in Biology from the University of Illinois, and an M.S. and Ph.D. in Biological Materials from Northwestern University.  He is a founding fellow and past-President of the Academy of Dental Materials.  He is a past-President of the Dental Materials Group of the International Association for Dental Research.  He is a past-President of the American Association for Dental Research (now American Association for Dental, Oral and Craniofacial Research). He is the recipient of the IADR Distinguished Scientist Wilmer Souder Award from the Dental Materials Group of the IADR, the Founders Award from the Academy of Dental Materials, and the Hollenback Award from the Academy of Operative Dentistry. He is an honorary member of the American College of Dentists and the Oregon Dental Association. He is a fellow of the American Institute of Medical and Biological Engineering. He serves on the editorial board of ten journals, and is Editor-in-chief of a new journal published by the ADA and Elsevier entitled, JADA Foundational Science. He is a past Associate Editor of the Journal of Dental Research and Odontology. He has served as a regular member of the Oral, Dental and Craniofacial Sciences Study Section [ODCS] of the NIH/NIDCR. He has authored a textbook entitled “Materials in Dentistry. Principles and Applications.” He is co-editor of a textbook entitled “Craig’s Restorative Dental Materials.” Currently in its 14th edition. He is a co-editor of a textbook entitled “Summitt’s Fundamentals of Operative Dentistry. A Contemporary Approach,” now in its fourth edition. He has published and lectured extensively on dental materials, including dental composites, adhesives, amalgam, and practice-based dental research.  He has provided continuing education at annual meetings of the ADA, British Dental Association, California Dental Association, Chicago Midwinter, Midwest Dental Conference, Oregon Dental Conference, Pacific NW Dental Conference, Southwest Dental Conference, Yankee Dental Congress, and to other professional dental organizations. His current research interests are in developing new monomers for enhanced dental composites, studying the factors that affect biofilm formation around dental composite restorations leading to the recurrence of caries lesions, and the use of bioactive glasses as potential antimicrobial and remineralizing agents in resin-based dental materials. His research is funded by the NIH/NIDCR as well as private industry.  He also is actively involved in the establishment and operation of networks designed to conduct dental clinical research in the private practice setting, and most currently was involved in a large scale clinical study in the NIH-funded National Dental Practice-based Research Network (The Network) investigating the characteristics and progression of cracked teeth. 


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A Primer for “Bioactive” Dental Materials

Dentistry is moving toward a time when restorative materials exhibit properties beyond being inert or biocompatible. Choices are appearing that are designed to create positive effects within the oral environment. Materials have components that are antimicrobial, mineralizing, regenerating or some combination of those outcomes. These materials are often termed &ldquo\;bioactive&rdquo\;. The purpose of this evidence-based Quality Resource Guide (QRG) is to provide clarity for the dental provider around the concept of &ldquo\;bioactive&rdquo\; materials used for restorative dentistry by describing and discussing the types of available materials, their intended uses, and their modes of action. The QRG will identify the types of materials that have been referred to as &ldquo\;bioactive&rdquo\; and their modes of action. It will describe how certain &ldquo\;bioactive&rdquo\; materials claim to exert effects on bacteria or contribute to the mineralization of tooth structures. The QRG will serve as an essential resource for practitioners as they assess new restorative materials coming on the market with their suppliers and colleagues, striving to maximize the success of restorative outcomes and the oral health of their patients.

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