Quality Resource Guide
l
Temporomandibular Disorders 3rd Edition
2
www.metdental.com
between a number of cranial and cervical nerves,
including the trigeminal system, complicating the
evaluation of the patient with orofacial pain. This
shared neurologic circuitry makes the etiology
of orofacial pain difficult to diagnose.
6
Confusion
regarding diagnostic and clinical decision-making
is compounded by the fact that signs associated
with TMD occur quite commonly in the general
population. Therefore, decisions regarding who
should, and who should not, be treated may
be challenging. Seventy-five percent of those
evaluated in a non-patient study exhibited at least
1 sign (joint noise or palpation tenderness) and
33% exhibited at least one symptom
7
, while only
3.6% to 7% of individuals with TMD are in need of
treatment.
7,8
Pain in other regions of the body, and more
specifically
in
the
head
and
neck,
share
commonalities or are comorbid with TMD.
Headache and ear-related symptoms are frequent
complaints among TMD patients.
9-14
Pain in other
regions of the body including other joints have
been associated with TMD.
15,16
A study of a TMD
patient population indicated that 75% also reported
concomitant neck pain. Seventy-two percent of the
study group was experiencing pain in areas of the
head other than the masticatory region, and 72%
reported back pain.
17
It has also been reported
that high pain intensity and long pain duration
increase the probability of having co-existing pain
and comorbidities in this patient population.
18
Who is at Risk?
The most common age group found to be affected
is between 15 and 45 years of age (mean: 33.9
years).
19
Demographic data from clinically based
studies indicate that TMD symptoms are least
prevalent in the young and seem to decrease
after the age of 45. A significant sex bias exists
among patient populations of 6:1 to 9:1, with
females more represented than males.
20,21
The
literature on experimentally-induced pain indicates
sex differences, with females displaying greater
sensitivity.
22
Sex differences are also noted in
epidemiological studies with females reporting
more severe pain, more frequent pain, and pain of
longer duration.
23,24
Introduction
In a general population survey involving 805
individuals having a persistent pain disorder, it
was revealed that more than four out of 10 people
had not found adequate relief, saying their pain is
out of control— despite having the pain for more
than 5 years and switching doctors at least once.
1
Therefore, it should not be a surprise the most
common reason patients seek medical or dental
care in the United States is due to pain. Lipton and
others, in a study of 45,711 households, revealed
that 22% of the U.S. population experienced
orofacial pain on more than one occasion in a 6
month period. Odontogenic pain was the most
frequently reported condition.
2
Non-odontogenic
pain involving the orofacial region such as
temporomandibular joint (TMJ) pain, face pain,
and neuropathic conditions were also commonly
reported. Since each pain disorder is unique,
establishing an accurate and complete differential
diagnosis is fundamental. It is mandatory that dental
practitioners develop the necessary scientific and
clinical expertise on which he/she may base
diagnostic and management approaches.
Temporomandibular disorder (TMD) is currently
viewed as a group of musculoskeletal and
neuromuscular conditions that involve the TMJs,
the masticatory muscles, and all associated
tissues.
3
TMD has been identified as one of the
most common non-odontogenic pain complaints
and is the second most frequent cause of
musculoskeletal pain and limitation, only preceded
by low back pain.
2
Population-based studies
indicate the prevalence of TMD-related pain is
12%.
2
The National Institutes of Health reported
that 10 million Americans suffer from TMD related
complaints each year.
5
TMD Signs and Symptoms
The cardinal signs (objective indicators) and
symptoms (subjective experiences) of TMD are:
pain in the temporomandibular region; limitation
or disturbance in mandibular movement and/or
masticatory functional ability; and, TMJ sounds.
However, this description is far too simplistic.
The complexity of neural pathways in the head
and neck region provides dynamic interactions
Arthrogenous (joint related) TMD
The most common sign of TMD has been identified
as TMJ clicking, due to displacement of the
articular disc. General population based studies
have reported clicking, popping or crepitus to
occur in about 50% of those studied.
8
A magnetic
resonance image (MRI) study identified that 86%
of a TMD patient population demonstrated disc
displacement. However, 33% of the non-patient
controls also had disc displacement.
25
Although
the concept of natural progression of TMD has
been purported in the past, there is a lack of
evidence supporting the concept that TMJ joint
clicking progresses to locking and degeneration,
or that arthritic changes develop in joints that lock.
It has been reported that most degenerating joints
tend to become non-painful with time; although, as
many as 16% of these individuals may experience
pain long-term.
26
Myogenous (muscle related) TMD
Muscle-related signs and symptoms are very
common in the general population and account
for the most common subgroup of patients with
TMD.
27,28
Definitive theories do not presently
exist that totally explain why masticatory muscles
become painful, their associated symptomatology,
or the cause(s) leading to chronicity. Furthermore,
there is no single identifiable etiologic factor;
therefore myogenous pain is considered complex
and multifactorial, making it more challenging to
identify risk factors and their unique contributions
to the process.
29
It is important to recognize there
exists a dynamic relationship between the function
of the masticatory and cervical muscles. Due to
this relationship, these regions must be thoroughly
assessed during routine TMD patient evaluations.
In fact, cervical tenderness scores have been
shown to differentiate between TMD patients and
controls and between different TMD diagnoses.
30
The putative mechanisms behind masticatory
myalgia typically include overuse of a normally
perfused muscle or ischemia of a normally working
muscle, sympathetic reflexes produciing changes
in vascular supply and muscle tone, or changes
in psychological and emotional states.
31
Individual
variations in muscle anatomy, biomechanics, and