Quality Resource Guide
l
Management of the Patient with Dentin Hypersensitivity
7
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protective hydroxyapatite-like layer on the dentin
surface. A number of clinical studies investigating
efficacy of NovaMin have reported immediate
significant reduction of pain and a relief of dentinal
hypersensitivity that persisted 28 days after scaling
and root planning procedures were completed.
37,57-60
3. Prescription Dentifrices
PreviDent
®
5000 Sensitive (1.1% Sodium Fluoride,
5% Potassium Nitrate) is a prescription strength
(5000 ppm fluoride) toothpaste formulated for
sensitive teeth. It has a unique liquid gel formula that
enables faster fluoride dispersion than paste-form
toothpaste. It is recommended for use twice daily in
place of regular toothpaste.
61-64
Cavex Bite & White ExSense (Cavex Holland BV) is
another prescription dentifrice that has shown fast
and long-lasting relief from dentin hypersensitivity. It
has a blend of hydroxyapatite and hydro-dispersing
clay that has unique properties to ensure accelerated
dispersion, helping boost hydroxyapatite penetration.
It was reported that the hydroxyapatite penetrates
deep into the tubules and micro-cracks in the
enamel completely sealing off the areas causing
sensitivity.
65,66
Products combining 5,000 ppm sodium fluoride and
NovaMin technology have been introduced to the
market in the past few years. These products purport
that they provide significant dual benefits for patients
targeting caries and dentin hypersensitivity.
4. Bonding Agents
Light-cured bonding agents are used in the dental
offices to immediately block open dentinal tubules
and reduce dentin hypersensitivity. CLEARFIL
®
SE
Protect (Kuraray Dental, Okayama, Japan) is a
self-etching long-term fluoride release light cure
monomer that has an antimicrobial benefit. The
ability to create a cross-linked protein leads to
plugging of the dentinal tubules. Dentists have
reported satisfactory clinical results.
67
Gluma
®
Desensitizer and Gluma
®
Desinstizer
PowerGel (Heraeus Kulzer, Hanau, Germany) have
been on the market for over 10 years and used
worldwide to reduce dentin hypersensitivity. They
have been reported to have the ability to penetrate
up to 200μm into the exposed dentinal tubules
where they form multiple layers of protein septa
preventing intratubular fluid movement following
osmotic
changes.
68,69
Calm-It™
Desensitizer
(DENTSPLY Caulk) has a similar concept.
5. Lasers
Various laser (light amplification by stimulated
emission of radiation) types have been tested and
used for dentin hypersensitivity treatment, including;
Nd:YAG; Er:YAG; CO2; He-Ne; and GaAlAs diode
lasers. The effectiveness ranges reported vary
widely, as do the laser type and parameters used.
Lasers were used with various energy settings and
with wavelengths ranging from 632.8 nm (He-Ne)
to 10,600 nm (Er:YAG, CO2).
10,21
The mechanism
of action of lasers in treating hypersensitivity is
not clear, but it has been proposed that lasers
coagulate the proteins inside the tubules and block
the movement of fluid. For low output-power lasers
(diode laser=780-900 nm or He-Ne lasers=632.8
nm) the desensitizing effect seems to be related
to laser activity at the nerve level mediating an
analgesic effect related to depressed nerve
transmission.
70
The desensitizing effect of the
middle output-power lasers (Nd:YAG, CO2, and
Er:YAG) could be related to an interaction with the
dental pulp, causing a photobiomodulating (PBM)
effect, increasing the cellular metabolic activity
of the odontoblasts and occluding the dentinal
tubules with tertiary dentin production. PBM is the
application of light delivered by a low power laser
of light-emitting diode to promote tissue repair,
reduce inflammation or induce analgesia.
6,21,70
A
systematic review comparing laser therapy with
desensitizing agents suggests that lasers may have
a slight clinical advantage over topically applied
medicaments, especially in severe cases.
21
A recent
study explored the possible synergistic effect of
lasers and topically applied treatments.
71
Long-Term Management of
Dentin Hypersensitivity
Treatment of dentin hypersensitivity, at-home or
in-office, is only one aspect of the management of
dentin hypersensitivity. It is imperative in achieving
lasting comfort to consider effective plaque control,
strategies to enhance salivary flow, increase
salivary pH and improve its buffering capacity and
implement dietary modifications as appropriate.
Controlling dentin hypersensitivity is an ongoing
challenge that requires dentist intervention AND
patient cooperation.
Conclusion
The management of dentin hypersensitivity
can be carried out at home with over
the counter agents containing potassium
salts or other effective compounds and
in-office using a variety of treatments
including topically applied desensitizing
agents
(fluoride,
potassium
nitrate,
oxalate, calcium phosphates), adhesives
and lasers. Prevention and at-home
treatments are a good place to start.
They can later be supplemented with
in-office treatments if needed. However,
with the conflicting findings about both
self-applied and professional methods,
evidence-based analysis cannot currently
proclaim one agent or technique to be
superior in the management of dentin
hypersensitivity. Clinicians should initiate
therapy for dentin hypersensitivity with
conservative approaches, progressing to
more aggressive, time-consuming or costly
procedures if they are unsuccessful.